Richard A. Posner writes that "Traditionally, rape was the offense of depriving a father or husband of a valuable asset — his wife's chastity or his daughter's virginity".  Historically, rape was seen in many cultures (and is still seen today in some societies) as a crime against the honor of the family , rather than against the self-determination of the woman. As a result, victims of rape may face violence, in extreme cases even honor killings, at the hands of their family members.   Catharine MacKinnon argues that in male dominated societies, sexual intercourse is imposed on women in a coercive and unequal way, creating a continuum of victimization, where women have few positive sexual experiences. [xix] Socialization within rigid gender constructs often creates an environment where sexual violence is common. [xx] One of the challenges of dealing with sexual violence is that in many societies women are perceived as being readily available for sex, and men are seen as entitled to their bodies, until and unless women object.   [xxi]
The story begins with the protagonist, Fujimori Ayumu, waking up in the nurse's office of a place they are unfamiliar with. They discover they are inside Kaihō Gakuen, where after meeting all the other students, they find out all the students have been transferred there and sealed inside the building. The students meet the . Monodora (モノドラ), a floating Monokuma -like head with cat ears, a tail, and a gold bell. Monodora introduces themself as the high school's president, and tells the students that they are now to be involved in a Mutual Killing Game. After a murder is committed, a class trial will be held, where the murderer, " Kuro " (クロ Black) will have to defend themselves against the " Shiro " (シロ White), and try to convince the other students that someone else was the murderer. If they are successful, they will be allowed to leave. If they fail, they will be executed .